Epithalon
Also known as epitalon, AEDG peptide
Marketed on telomere and longevity claims that rest almost entirely on decades-old work from a single research group.
$30–90 per vial on grey markets.
How it works
A synthetic tetrapeptide proposed to stimulate telomerase activity and regulate pineal melatonin secretion. Nearly all supporting work originates from one Russian research lineage and has not been independently replicated at any scale.
How it's used
No approved use, no independent replication, no meaningful human safety data. There is no protocol here worth publishing.
Trade-offs
In favour
- Very low reported acute toxicity in the available studies
Against
- Essentially no independent evidence
- Longevity claims are unsupported by anything replicated
- Unregulated product
Risks and side effects
- Deliberately increasing telomerase activity has an obvious theoretical cancer concern
- Unverified purity and sterility
- No long-term human safety data whatsoever
How good is the evidence?
Claims rest on a narrow, largely unreplicated body of work. Treat marketing around this as marketing.
Sources
Sources point to guideline bodies and literature searches rather than single papers, so they stay accurate as the evidence moves.