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Injectable
InjectableFacial structure Prescription

Botulinum Toxin

Also known as Botox, Dysport, neuromodulator

The most performed cosmetic procedure in the world. Predictable, temporary, and easy to overdo.

Evidence
Very strong
Typical cost
$200 – $800
Permanence
Temporary
Timeline
Onset at 3–5 days, full effect at 2 weeks, wearing off from month 3.

US $10–20 per unit. Glabella typically 20–25 units; masseter 40–60 units. Expect $300–800 per session.

How it works

Blocks acetylcholine release at the neuromuscular junction, temporarily paralysing the injected muscle. Relaxing the muscles that fold the skin softens dynamic lines and prevents them etching into static wrinkles. Placement in the masseter shrinks the muscle through disuse atrophy.

How it's used

Dosed in units by area. Common sites are the forehead, glabella, crow feet, masseter for jaw slimming, and the platysma. Use an injector who understands facial anatomy — a bad forehead treatment drops the brow and makes you look heavier-lidded. Start conservatively; you can always add more at the two-week review.

Trade-offs

In favour

  • Reliable and predictable results
  • No downtime
  • Genuinely preventive against static line formation
  • Fully reversible by simply waiting
  • Masseter treatment slims a wide lower face

Against

  • Requires repeat treatment every 3–4 months, indefinitely
  • Cost compounds over a lifetime
  • Over-treatment produces a frozen, expressionless look
  • Masseter atrophy can cause midface hollowing over years of use

Risks and side effects

Read before deciding
  • Eyelid or brow ptosis from diffusion into the levator — temporary but lasts weeks
  • Asymmetry
  • Headache after treatment
  • Bruising at injection sites
  • Antibody resistance with frequent high-dose use
  • Long-term masseter treatment can weaken chewing and alter facial support

Recovery

None. Avoid lying down, exercise and rubbing the area for 4 hours. Bruising, if any, resolves in a few days.

How good is the evidence?

Very strong
Extensive high-quality evidence and guideline support.

Enormous randomised trial and real-world safety base; one of the best-characterised cosmetic interventions available.

Sources

Sources point to guideline bodies and literature searches rather than single papers, so they stay accurate as the evidence moves.

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